Complexigen, LLC - Unraveling the Complexities of Life....
  • John M. Greene, Ph.D. - President and Chief Scientific Officer

John Greene has been a professional bioinformatics scientist for over 13 years.  Trained as a molecular biologist, he left the lab bench in June 1996 while employed at Human Genome Sciences, and was the first person there to hold the Bioinformatics Scientist title.  Subsequently, he was a Senior Staff Scientist in Bioinformatics Analysis at Gene Logic, before joining government systems integrator and consulting firm SRA International in late 1999

He has been a Principal and Director of Bioinformatics there since late 2000. Among his engagements with SRA International have been: Project Manager for The Cancer Genome Atlas (TCGA) Data Coordination Center and Data Portal; Project Manager for the NIEHS SRA contract; Task Lead for the NCI Microarray Database (mAdb); assignments with NIMH, the Netherlands Cancer Institute, and the Genome Institute of Singapore; Technical Coordinator for the National Database for Autism Research (NDAR); Project Manager for the NCI Center for Bioinformatics Pathway Interaction Database (an NCI collaboration with Nature) and the Cancer Genomics Workbench Translational Research Support projects; Program Manager for SRA's NCI caBIG Support Service Provider Program award for deployment support, and Principal Investigator and Project Manager for the $14.6M NIAID Enteropathogen Resource Integration Center (ERIC)—where he is the only Principal Investigator from industry in this biodefense informatics program. 

Dr. Greene is a Phi Beta Kappa graduate of MIT, where he received a B.S. in Life Sciences in 1983 and spent two years in the laboratory of Institute Professor and Nobel Laureate Phillip A. Sharp, winning the John L. Asinari Award for Undergraduate Research. He earned his Ph.D. in Genetics on an NSF Graduate Fellowship under the supervision of Professor Robert E. Kingston (now VIce-Chair of Genetics) at Harvard University in 1989, and was a National Research Council Research Associate in Biotechnology for his postdoctoral fellowship with Dr. Igor Dawid at NICHD. In addition, he holds a Professional Certificate in Information Systems from The George Washington University.  Duirng his education, he was trained by six Nobel laureates (Drs. Sharp, Horvitz, Luria, Fire, Baltimore, and Szostak).

Dr. Greene is a charter member of the International Society for Computational Biology, was the sole student from biotech in the 1997 Computational Genomics class at Cold Spring Harbor Laboratory, and for over ten years has been Adjunct Faculty in the M.S. in Bioinformatics program of The Johns Hopkins University’s Advanced Academic Programs, teaching 410.634 Practical Computer Concepts for Bioinformatics and 410.712 Advanced Computer Concepts for Bioinformatics.  He was a member of the Maryland Governor's Workforce Investment Board (Biosciences Steering Committee), and holds 27 U.S. patents on novel genes, 21 of which are first author. 

An author of 19 peer-reviewed papers, he has also authored three book chapters and has been interviewed on bioinformatics by Science, BioInform, Genomics and Proteomics, Bio-IT World, and Chemical and Engineering News.